How To Start A Pharmacy

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As you consider how to start a pharmacy, there are dozens of critical questions to answer. What kind of business plan is necessary? How much capital will you need? How does one go about setting up a store? How much inventory is needed? How will you manage all the complexity of patient care? Most importantly, how will you compete for customers with the big box retail chains and other community pharmacies?

To answer these questions and get invaluable perspectives on how to start a pharmacy, it’s important to have a trusted partner who can guide you through the critical decisions and help you navigate the many tasks involved in establishing a new healthcare business in. That’s where VentureRx from H. D. Smith can help.

How to start a pharmacy with help from H. D. Smith.

H. D. Smith is the largest independent wholesale pharmacy supplier in the United States. In addition to providing competitive pricing on medicines and independent pharmaceutical supplies, we offer a suite of business solutions that includes VentureRx, a program for those who want to know how to start a pharmacy, or to purchase or sell an existing pharmacy.

VentureRX provides services and solutions in the following areas:

  • Marketing. Our experts in independent pharmacy advertising can help you determine how to start a pharmacy with a strong brand, a social media plan and an attractive website with technology for online prescription refills. We also provide independent pharmacy branding and marketing services, market research and loyalty programs to help reward frequent shoppers.
  • Managed care. We provide access to the Arete Pharmacy Network, which offers a comprehensive portfolio of programs and solutions designed to manage the financial, quality and operational aspects of the pharmacy more efficiently.
  • Store design and merchandising. From store layout and design to a pricing and planning, merchandising and front-end marketing, we help you understand how to start a pharmacy that can immediately attract and serve customers.
  • Patient care. We provide access to software for managing patient care more effectively and efficiently, incorporating pharmacy best practices and working with pharmaceutical third-party logistics (pharmaceutical 3PL) more successfully.

How to start a pharmacy by buying an existing business.

Perhaps you don’t need to know how to start a pharmacy, but rather how to purchase an existing business. VentureRx can help here as well. Our experts can walk you through every stage of the transaction to ensure a smooth and seamless buying process.

Our services include research into available pharmacies for sale, identifying financing options and potential partners, providing purchasing guidance and assistance, and establishing a wholesale contract suited to your business needs.

Learn more about how to start a pharmacy with H. D. Smith.


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Learn more about how H. D. Smith can help you achieve your business goals.

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  • Customer Experience

    Kevin Sexton
    Danny's Drugs
    Oneida, TN
    H. D. Smith customer for 7 years

    “I am satisfied with my overall customer experience. My sales manager is a treasure and has helped me beyond words!”

    November 16, 2017

  • Excellent!

    Les Williams
    Terry's Family Pharmacy
    Verona, NJ
    H. D. Smith customer for 32 years

    “We always receive an accurate delivery. There is never a shortage, and no question, there is never a mistake in the pick. The return system is the best, and again, no question how it works. Credits are also given so fast.”

    February 3, 2017

  • Never Too Busy to Help

    Brian Ambrefe
    Village Pharmacy
    Lynnfield, MA
    H. D. Smith customer for 2 years

    “No matter who I call and no matter how busy they are, I am always made to feel that I am the only thing that matters to customer service. Believe me, that goes way beyond the customer service of our previous suppler.”

    January 9, 2017

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  • Dannys Drugs

    Customer Spotlight

    “Customer service has always been wonderful – I speak to the same people every time who know me by name. I’ve never had a question or complaint that hasn’t been resolved in a reasonable amount of time.” - Kevin Sexton, PharmD, Co-owner, Danny’s Drugs 

    Danny's Drugs knows how to stand out and make an impact in its community. 

    Learn how it took the right business deal with a personal touch to solidify this rewarding partnership.

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  • Maria Valeriano

    Team Member Spotlight

    "Every day at H. D. Smith, I feel valued and respected. By far this is the best company I have ever worked for, and I cannot imagine ever finding a company that values its employees as much as H. D. Smith does.

    With its strong core values, family feel and employee development, there really is no better place to work."

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