340B Prime Vendor

Community pharmacies and the 340B Prime Vendor Program

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For community pharmacists, reaching customers who are eligible for discounted medicines through the 340B Prime Vendor Program can help improve profitability while serving patient populations more effectively.

The 340B Prime Vendor Program was established to provide healthcare providers with access to low-cost medications, enabling them to better serve patients in under-resourced communities who may not otherwise be able to afford the medication they need.

With a reputation for providing excellent service to the community, independent pharmacies are often the best candidate for reaching out to entities within their communities that are eligible for the 340B Prime Vendor Program. In doing so, independents can perform a valuable service by connecting more patients with the healthcare they require while also creating an additional revenue stream that can help community pharmacies to remain profitable and successful.

To provide discounted medicines to covered entities, independent pharmacies need a relationship with a pharmaceutical supplier that participates in the 340B Prime Vendor Program. For thousands of independents nationwide, H. D. Smith is the 340B Prime Vendor supplier of choice.

H. D. Smith: a leading participant in the 340B Prime Vendor Program.

Since 1954, H. D. Smith has been dedicated to helping independent pharmacies better serve their patient communities. Today, we are one of the largest independent focused pharmaceutical wholesale distributors in the US. We offer access to competitively priced generics, brand pharmaceuticals, specialty medicines, home healthcare products, consumer products and pharmacy supplies, along with a suite of value-added solutions for improving pharmacy margin basis points and achieving a pharmacy five star rating.

As a participant in the 340B Prime Vendor Program, we make it easy for independents to offer access to affordable medications and supplies, including vaccines, contraceptives, nicotine replacement therapy, antibiotics, diabetic products and injectables.

Benefits of choosing H. D. Smith as your 340B Prime Vendor source.

When choosing H. D. Smith as the primary source for products eligible through the 340B Prime Vendor Program, independent pharmacies are able to:

  • Partner with a pharmaceutical supplier dedicated to serving the needs of community pharmacies.
  • Buy generic drugs online through H. D. Smith’s PharmaGen portfolio, one of the most robust collections of generic medicines in the market.
  • Learn how to increase pharmacy profits, streamline operations and simplify financial, quality and operational aspects of the business.
  • Get expert advice on how to start a pharmacy, by a pharmacy or sell a pharmacy.

Learn more about the 340B Prime Vendor Program and H. D. Smith, and about solutions for pharmaceutical third-party logistics (3PL).


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  • Customer Service

    Christina Price
    Ray's Pharmacy
    Arlington, TX

    “My experience with customer service is that they ROCK! They are very courteous and helpful in every way. I like dealing with them because they take care of things on the spot. ”

    November 29, 2016

  • Exceptional Service

    Mannie C.
    Mercy Pharmacy
    Brooklyn, NY

    “Our sales rep is AMAZING!! He truly goes above and beyond to make our ordering process seamless. Just wanted to take a moment to commend and thank H. D. Smith for providing us with such an amazing rep!”

    November 30, 2017

  • Extraordinary Service

    Jenny Dowhower, Pharmacy Buyer
    Schneck Medical Center
    Seymour, IN
    H. D. Smith customer for 62 years

    “Our sales specialist has always gone above and beyond with our annual inventory process, but this week she went even higher. We have recently gone 340B, and she has helped keep my anxiety down and has been with us physically and on teleconferences. She's the best!”

    November 8, 2016

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    With its strong core values, family feel and employee development, there really is no better place to work."

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    “Customer service has always been wonderful – I speak to the same people every time who know me by name. I’ve never had a question or complaint that hasn’t been resolved in a reasonable amount of time.” - Kevin Sexton, PharmD, Co-owner, Danny’s Drugs 

    Danny's Drugs knows how to stand out and make an impact in its community. 

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